Find Resorts & Hotels with Spas in Cayo Guillermo

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Pick from 2 Cayo Guillermo Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Iberostar Daiquirí - All inclusive
4.0 star property
6.6 out of 10, (41)
"The location of the hotel, staff, food and entertainment are great. We felt it’s a well designed hotel (Believe just over 300 rooms) as it never felt overcrowded nor overlooked. The staff are wonderfully helpful and friendly and plenty around. "
Iberostar Daiquirí - All inclusive
Club Cayo Guillermo - All Inclusive
3.5 star property
6.0 out of 10, (1)
"В целом неплохо. Отель вроде хороший но номера грязные и убитые. Кормят нормально. На пляже водоросли "
Club Cayo Guillermo - All Inclusive
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Cayo Guillermo?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Check out the beaches in Cayo Guillermo - worth a picture or two! Spa hotels are the perfect way to break away from your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Cayo Guillermo?
Among Expedia’s 5 accommodation options in Cayo Guillermo, there are 3 spa hotels.
What's there to see and do in Cayo Guillermo?
Experience Cayo Guillermo with a stop at Cayo Guillermo Beach and Parque Natural el Bagá.
What is a Cayo Guillermo spa hotel?
Spa hotels in Cayo Guillermo provide lodging and have a full on-site spa offering services such as therapies as well as body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.