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Find All Upstate South Carolina Hotels
We have found 2598 Upstate South Carolina Hotels
- Days Inn by Wyndham Seneca / Clemson Area
- Quality Inn Clemson near University
- Holiday Inn Express Anderson by IHG
- Fairfield Inn & Suites Seneca Clemson Univ Area
- Home2 Suites by Hilton Anderson Downtown
- HomeTowne Studios by Red Roof Spartanburg - Asheville Highway
- Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
- Holiday Inn Anderson by IHG
- Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG
- WoodSpring Suites Greenville Simpsonville
- Home2 Suites by Hilton Greenville Airport
- Baymont by Wyndham Easley/Greenville
- Country Inn & Suites by Radisson, Anderson, SC
- Courtyard Marriott Clemson
- WoodSpring Suites Greenville Central I-85
- Residence Inn by Marriott Spartanburg
- Holiday Inn Express & Suites Greenville-Spartanburg (Duncan) by IHG
- Red Roof Inn Spartanburg - I-85
- Days Inn by Wyndham Greenville South/Mauldin
- Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
- Sleep Inn
- Hampton Inn & Suites Clinton - I-26
- Comfort Suites Simpsonville - Greenville
- Hampton Inn Easley
- Hampton Inn Anderson/ Alliance Business Park
- Quality Inn
- Residence Inn by Marriott Greenville Downtown
- Home2 Suites by Hilton Duncan
- Super 8 by Wyndham Greer/Spartanburg Area
- Hampton Inn Gaffney
- Extended Stay America Select Suites - Greenville - Airport
- Microtel Inn by Wyndham Duncan/Spartanburg
- Baymont by Wyndham Anderson Clemson
- Hampton Inn Simpsonville
- Days Inn by Wyndham Greenville
- Staybridge Suites Greenville I-85 Woodruff Road by IHG
- Fairfield Inn & Suites by Marriott Anderson Clemson
- Extended Stay America Select Suites Greenville Haywood Mall
- Swamp Rabbit Inn
- Quality Inn & Suites Easley - Greenville
- USA Economy Lodge
- Hampton Inn Greenville/Travelers Rest
- WoodSpring Suites Spartanburg Duncan I-85
- Comfort Suites Clinton near Presbyterian College
- Red Roof Inn & Suites Duncan
- Quality Inn Duncan - Spartanburg West
- Quality Inn Clinton - Laurens I-26
- Holiday Inn Spartanburg Northwest by IHG
- Days Inn by Wyndham Simpsonville
- Hometowne Studios Greenville
- Super 8 by Wyndham Piedmont Greenville Area
- Rodeway Inn
- Motel 6 Greenville, SC - I-85 Near Downtown
- Quality Inn Union US Hwy 176
- Residence Inn by Marriott Anderson Clemson
- Hampton Inn Anderson
- Super 8 by Wyndham Anderson/Clemson Area
- Baymont by Wyndham Duncan/Spartanburg
- Homewood Suites by Hilton Greenville
- Swamp Rabbit Inn Travelers Rest
- Baymont by Wyndham Gaffney
- Red Roof Inn Greenville
- Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
- Liberty Hall Bed and Breakfast
- Motel 6 Simpsonville, SC - Greenville
- Residence Inn by Marriott Greenville-Spartanburg Airport
- Days Inn by Wyndham Clinton / Laurens I-26
- Budget Inn Express
- Residence Inn by Marriott Spartanburg Westgate
- Quality Inn
- Red Roof Inn Spartanburg – I-26
- The Bleckley Inn
- Suburban Studios Spartanburg - I-26
- Motel 6 Spartanburg, Sc – Northwest / Business 85
- Candlewood Suites Greenville by IHG
- BEAUTIFUL Newly Built Retreat w/Private Marina Boat Slip at Upper Lake Keowee!!!
- Days Inn by Wyndham Spartanburg
- Rodeway Inn Expo Center
- Quality Inn Gaffney I-85
- Hotel Domestique
- Econo Lodge
- Americas Best Value Inn Anderson, SC
- Red Roof Inn Gaffney
- Rodeway Inn & Suites
- Rodeway Inn
- Econo Lodge
- Sleep Inn Gaffney at I-85
- ✨ Steps from the Swamp Rabbit Trail, Tandem Coffee, Topsoil and more.
- Studio 6 Greenville, SC - I-85 Near Downtown
- Rodeway Inn
- Pettigru Place Bed & Breakfast
- Private Suite in Downtown Simpsonville
- Modern Remodeled Farmhouse - Great Location
- Tanglewood Inn
- Clemson University's James F. Martin Inn
- Super 8 by Wyndham Gaffney
- Whole Hearts Bed and Breakfast
- Original Family Farmhouse just 2 mins off I-26 & 8 mins from d-town Spartanburg!