Find 5 Star Hotels in Ohio River Valley from SAR 281
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Ohio River Valley 5 Star Hotels
Tonight
Tomorrow
Next weekend
In two weeks
Compare Ohio River Valley 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Conrad Indianapolis
Conrad Indianapolis
9.2 out of 10, Wonderful, (1001)
The price is SAR 792
SAR 927 total
includes taxes & fees
26 May - 27 May

Louisville Bourbon Inn
Louisville Bourbon Inn
10.0 out of 10, Exceptional, (13)
The price is SAR 994
SAR 1,154 total
includes taxes & fees
27 Apr - 28 Apr

Jungle Fever
Jungle Fever
7.4 out of 10, Good, (3)
The price is SAR 1,315
SAR 1,678 total
includes taxes & fees
28 Apr - 29 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Ohio River Valley.

Omni Louisville Hotel
400 S. 2nd Street, Louisville, KY
The price is SAR 597 per night from May 26 to May 27
SAR 597
SAR 703 total
includes taxes & fees
26 May - 27 May
9/10 Wonderful! (1,403 reviews)
Still don't see what you're looking for?
See all properties in Ohio River Valley.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Ohio River Valley
Lively festivals, beloved sports teams, and top sights from Kings Island to Gainbridge Fieldhouse—discover Ohio River Valley, a historic destination also famous for its college vibe.

Explore a world of travel with Expedia
Explore a world of travel with Expedia
Ohio River Valley Hotels by Star Rating
Stay near popular Ohio River Valley attractions
- Hotels near Kings Island
- Hotels near Ark Encounter
- Hotels near Indianapolis Motor Speedway
- Hotels near Gainbridge Fieldhouse
- Hotels near Ohio State University
- Hotels near Lucas Oil Stadium
- Hotels near Great American Ball Park
- Hotels near University of Illinois at Urbana-Champaign
- Hotels near Hocking Hills State Park
- Hotels near Indiana University Bloomington
- Hotels near Purdue University
- Hotels near Greater Columbus Convention Center
- Hotels near Columbus Zoo and Aquarium
- Hotels near Kentucky Exposition Center
- Hotels near Indiana Convention Center
- Hotels near Newport Aquarium
- Hotels near Easton Town Center
- Hotels near University of Cincinnati
- Hotels near University of Kentucky
- Hotels near University of Dayton
More Hotel Options in Ohio River Valley
- Adults Only Resorts & Hotels in Ohio River Valley
- Adventure Hotels in Ohio River Valley
- Beach Hotels in Ohio River Valley
- Boutique Hotels in Ohio River Valley
- Business Hotels in Ohio River Valley
- Casinos in Ohio River Valley
- Cheap Hotels in Ohio River Valley
- Family Hotels in Ohio River Valley
- Golf Hotels in Ohio River Valley
- Green Hotels in Ohio River Valley
- Historic Hotels in Ohio River Valley
- Hotel Wedding Venues in Ohio River Valley
- Hotel with a Concierge in Ohio River Valley
- Hotels with Bars in Ohio River Valley
- Hotels with Early Check-in in Ohio River Valley
- Hotels with Free Parking in Ohio River Valley
- Hotels with Hot Tubs in Ohio River Valley
- Hotels with Waterslides in Ohio River Valley
- Hotels with WiFi in Ohio River Valley
- Hotels with a Lazy River in Ohio River Valley
- Hotels with a Pool in Ohio River Valley
- Hotels with an Indoor Pool in Ohio River Valley
- Hotels with smoking rooms in Ohio River Valley
- Luxury Hotels in Ohio River Valley
- Pet-friendly Hotels in Ohio River Valley
- Resorts & Hotels with Spas in Ohio River Valley
- Romantic Hotels in Ohio River Valley
- Shopping Hotels in Ohio River Valley
- Ski Hotels in Ohio River Valley
- Waterpark Hotels in Ohio River Valley
- Winery Hotels in Ohio River Valley
More Accommodation Types in Ohio River Valley
- Vacation Homes in Ohio River Valley
- Apartments in Ohio River Valley
- Cabin Rentals in Ohio River Valley
- Motels in Ohio River Valley
- B&B in Ohio River Valley
- Cottages in Ohio River Valley
- Aparthotels in Ohio River Valley
- Condo Rentals in Ohio River Valley
- Lodges in Ohio River Valley
- Guest Houses in Ohio River Valley
- Farmstay in Ohio River Valley
- Villas in Ohio River Valley
- Resorts in Ohio River Valley
- RV Parks in Ohio River Valley
- Hostels in Ohio River Valley
- Inns in Ohio River Valley
- Safari Tentalow in Ohio River Valley
Explore more hotels
- Drury Plaza Hotel Cincinnati Florence
- The Westin Cincinnati
- Embassy Suites by Hilton Cincinnati RiverCenter
- Sheraton Indianapolis City Centre Hotel
- Hilton Columbus Downtown
- Crowne Plaza Louisville Airport Expo Ctr by IHG
- Marriott Indianapolis Downtown
- Bottleworks Hotel
- JW Marriott Indianapolis
- Olentangy Motor Inn
- Drury Inn & Suites Louisville East
- Sonesta Columbus Downtown
- Holiday Inn Columbus Dwtn-Capitol Square by IHG
- Hyatt Regency Columbus
- I Hotel And Illinois Conference Center
- Biddle Hotel and Conference Center
- Hyatt House Columbus OSU / Short North
- Holiday Inn Express and Suites Dry Ridge by IHG
- Bally’s Evansville Casino & Hotel
- Hyatt Place Columbus Dublin