Find 4 Star Hotels in Edisto Island, SC
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Compare Edisto Island 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.
Learn more about Edisto Island
Escape to relaxing Edisto Island! Enjoy its island views, beaches, and camping.

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Edisto Island Hotels by Star Rating
Stay near popular Edisto Island attractions
- Hotels near Edisto Beach State Park
- Hotels near Botany Bay Plantation
- Hotels near Botany Bay Plantation Heritage Preserve and Wildlife Management Area
- Hotels near Edisto Island Serpentarium
- Hotels near Plantation Course at Edisto
- Hotels near Edisto Island Museum
- Hotels near With These Hands Gallery
- Hotels near Bay Street
- Hotels near Folly Beach Fishing Pier
- Hotels near Marine Corps Air Station Beaufort
- Hotels near Henry C. Chambers Waterfront Park
- Hotels near James Island County Park
- Hotels near Angel Oak Tree
- Hotels near Kiawah Beachwalker Park
- Hotels near Freshfields Village
- Hotels near Night Heron Park
- Hotels near University of South Carolina-Beaufort
- Hotels near Turtle Point Golf Course
- Hotels near Folly Beach County Park
- Hotels near St. Johns Yacht Harbor
More Hotel Options in Edisto Island
- Adventure Hotels in Edisto Island
- Beach Hotels in Edisto Island
- Business Hotels in Edisto Island
- Family Hotels in Edisto Island
- Golf Hotels in Edisto Island
- Historic Hotels in Edisto Island
- Hotels with Bars in Edisto Island
- Hotels with Free Parking in Edisto Island
- Hotels with Hot Tubs in Edisto Island
- Hotels with WiFi in Edisto Island
- Hotels with a Pool in Edisto Island
- Romantic Hotels in Edisto Island
- Shopping Hotels in Edisto Island
Explore more hotels
- Quiet, oceanfront home with W/D, balcony, patio & great views - dog-friendly
- Beautiful home on Palmetto Blvd just steps from the beach !
- Oceanfront Showplace - Island Manor
- 4 Bedroom 2 Bath Ocean Front Vacation Rental on Edisto Beach
- Prime Location Less Than 1 Minute to Beach; Sun Deck; Screened Patio; CableTV/WiFi
- Oceanfront house with ocean views & beach access - near dining & golf
- 3 bedroom elevated chic home tucked among the trees~ The Paper House
- RARE 6 bedroom, 4 bath OCEANFRONT home, wonderful views & breathtaking sunsets!
- Welcoming villa with elegant screened porch
- Charming & sun-filled studio with great patio & W/D - close to beach
- Dog-friendly beach home with screened porch, charming interior, & W/D
- Private 4 bedroom home near beach and on golf course
- Edisto Condo
- A Room With a View-1 BR Efficiency Condo Close to Everything.
- Cottage: 3005 Palmetto Blvd.
- Beach home with huge lawn, open deck, covered patio & grill
- Comfortable Villa near the Beach w/ Balcony, WiFi, Washer/Dryer & Shared Pool
- Just released! OCEANFRONT, Four Bedroom 2 Bath Beach house ~ The Ravissant!
- The Sandy Pineapple! Direct Edisto Beach oceanfront with 4 bedrooms and 2 baths
- A Block and a Half to the Beach Dog-Friendly Home w/ Screened Porch & WiFi