Midtown, MO

St. Louis

Midtown
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Photo by Karissa Krull
Photo by Linda Garrison
Photo by Sophie R

Popular places to visit


Midtown Hotel Deals

Residence Inn by Marriott St Louis Downtown
Residence Inn by Marriott St Louis Downtown
3 out of 5
525 S Jefferson Ave, St. Louis, MO
The price is SAR 443 per night from Apr 20 to Apr 21
SAR 443
SAR 527 total
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free WiFi, a 24-hour fitness center, and parking (surcharge). Our guests praise the breakfast ...
7.8/10 Good! (1,003 reviews)
"Jessie at check it was fantastic! Very curteous, and gave us all the information we needed."

Reviewed on 6 April 2025

Residence Inn by Marriott St Louis Downtown
Element St. Louis Midtown
Element St. Louis Midtown
3 out of 5
3763 Forest Park Avenue, St. Louis, MO
The price is SAR 526 per night from Apr 20 to Apr 21
SAR 526
SAR 615 total
includes taxes & fees
20 Apr - 21 Apr
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
9/10 Wonderful! (475 reviews)
"We loved that the property has valet, kids loved the indoor pool since the weather wasnt perfect. Staff was AMAZING, we were on a road trip from south Mississippi and this was the second hotel we stayed in and it was 10 times better than the first. Breakfast was also AMAZING my husband who is usually ..."

Reviewed on 4 April 2025

Element St. Louis Midtown
Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
4 out of 5
315 Chestnut St, St. Louis, MO
The price is SAR 394 per night from Apr 18 to Apr 19
SAR 394
SAR 465 total
includes taxes & fees
18 Apr - 19 Apr
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy free WiFi, 3 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean ...
8.4/10 Very Good! (3,608 reviews)
"We were not prepared for offsite parking. The cost for valet was very high. We opted to park our car two blocks away in a garage and that still cost $25 for the night. We were traveling through with our infant daughter. Though a nice hotel, I'd say it isn't exceptionally family friendly as it was ..."

Reviewed on 8 April 2025

Hyatt Regency St. Louis at The Arch
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the Arch
3 out of 5
2 South 4th Street, St. Louis, MO
The price is SAR 450 per night from Apr 16 to Apr 17
SAR 450
SAR 527 total
includes taxes & fees
16 Apr - 17 Apr
Stay at this 3-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the breakfast and the pool ...
9.4/10 Exceptional! (2,458 reviews)
"Great breakfast and dinner options plus free drinks"

Reviewed on 6 April 2025

Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay
Clayton Plaza Hotel & Extended Stay
3.5 out of 5
7750 Carondelet Avenue, St. Louis, MO
Fully refundableReserve now, pay when you stay
The price is SAR 357 per night from Apr 13 to Apr 14
SAR 357
SAR 415 total
includes taxes & fees
13 Apr - 14 Apr
Stay at this 3.5-star business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,005 reviews)
"This is the third time I’ve stayed at the Clayton Plaza Hotel and it has been just right every time. The beds are comfortable. The breakfast is an excellent bonus. The rooms are spacious and clean. Our room had a huge shower and a bathtub."

Reviewed on 6 April 2025

Clayton Plaza Hotel & Extended Stay
Renaissance St. Louis Airport Hotel
Renaissance St. Louis Airport Hotel
4 out of 5
9801 Natural Bridge Road, St. Louis, MO
The price is SAR 443 per night from May 9 to May 10
SAR 443
SAR 518 total
includes taxes & fees
9 May - 10 May
Stay at this 4-star business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a free airport shuttle. Our guests praise the helpful ...
8.4/10 Very Good! (1,000 reviews)
"Very nice hotel! Convenient location and price!"

Reviewed on 7 April 2025

Renaissance St. Louis Airport Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Midtown

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The Gate

While there might not be top attractions in The Gate, you can explore the larger area and discover places like St. Louis Union Station and Enterprise Center.

The Gate
St. Louis which includes interior views

Downtown West

If you're spending some time in Downtown West, St. Louis Union Station and Enterprise Center are top sights worth seeing.

Downtown West
Lafayette Square which includes a house and a garden

Lafayette Square

The restaurants and shopping are a few reasons travelers visit Lafayette Square. Though there aren't many top sights in the neighborhood, you can visit St. Louis Union Station and Enterprise Center, a few notable attractions nearby.

Lafayette Square
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Shaw

4.5/5(3 area reviews)

While there might not be top attractions in Shaw, you can explore the larger area and discover places like Missouri Botanical Gardens and Arboretum and St. Louis Science Center.

Shaw
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Zoo and St. Louis Science Center are two attractions nearby that you can check out.

The Grove

Midtown, MO

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