Southern Minnesota Vacations
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Where to stay in Southern Minnesota
Find the best Southern Minnesota areas and neighborhoods for the activities you enjoy most. Learn more about Southern Minnesota
Downtown Rochester
2 out of top 10 points of interest in this area
4.5/5(250 area reviews)
If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Art Center are top sights worth seeing.
Find the Best Southern Minnesota Vacation Packages
Southern Minnesota Hotel Deals
Kahler Grand Hotel
20 2nd Ave Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is SAR 452 per night from Aug 27 to Aug 28
SAR 452
SAR 520 total
27 Aug - 28 Aug
includes taxes & fees
8.2/10 Very Good! (1,475 reviews)
"The bathroom was very small and the hot water was up and down to really cold to really hot while standing in the shower. Bed was comfortable and pillows too. Really like the cabinet in room,but frig didn't have a freezer to re freeze my cold packs. No room darking drapes to block out lights at night ..."
Reviewed on 29 July 2025
Med City Inn & Suites - Mayo Clinic Area
435 16th Ave Nw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is SAR 300 per night from Aug 10 to Aug 11
SAR 300
SAR 346 total
10 Aug - 11 Aug
includes taxes & fees
7.8/10 Good! (1,020 reviews)
"Close to where we had to go. The breakfast was good. The air conditioning in the room didn't seem to reach the bed. The pool/ hot tub was out of order."
Reviewed on 28 July 2025
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
1125 2nd St Sw, Rochester, MN
Fully refundableReserve now, pay when you stay
The price is SAR 360 per night from Aug 8 to Aug 9
SAR 360
SAR 415 total
8 Aug - 9 Aug
includes taxes & fees
8.4/10 Very Good! (835 reviews)
"Located right across street from St Mary’s"
Reviewed on 31 July 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Southern Minnesota
Winona State University
Enjoy the collegiate vibe when you visit Winona State University, during your trip to Winona. Stroll along the riverfront or experience the area's museums.
Forestville Mystery Cave State Park
Commune with nature and explore the great outdoors at Forestville Mystery Cave State Park during your travels in Preston. Wander the parks or discover the area's countryside.
Lake Shetek State Park
Commune with nature and explore the great outdoors at Lake Shetek State Park during your travels in The Lakes. Amble around the area's parks or experience its museums.