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Compare Sister Islands Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

2-bdrm Tropical Beach Paradise w/Pool, sandy beach, cabana, wifi & more!
2-bdrm Tropical Beach Paradise w/Pool, sandy beach, cabana, wifi & more!
10.0 out of 10, Exceptional, (63)

POOL, ON THE WATER, 2 QN BEDS, RAISED DECK, AC, WI-FI, KAYAKS
POOL, ON THE WATER, 2 QN BEDS, RAISED DECK, AC, WI-FI, KAYAKS
10.0 out of 10, Exceptional, (60)

POOL w/shade sails, sand beach, beach cabana, bikes, kayaks
POOL w/shade sails, sand beach, beach cabana, bikes, kayaks
10.0 out of 10, Exceptional, (14)

Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool
Luxury Oceanfront Villa, 2 Primary Suites + 3rd bdrm, Pool
10.0 out of 10, Exceptional, (56)

Stargaze from the Hot Tub, Waterfront Luxury Private Villa with Central AC
Stargaze from the Hot Tub, Waterfront Luxury Private Villa with Central AC
10.0 out of 10, Exceptional, (54)

Beach Front Paradise Home. Luxurious Funishings!
Beach Front Paradise Home. Luxurious Funishings!
10.0 out of 10, Exceptional, (63)

Lovely 'Sea Dreams Villa' w/ Private Beach & Deck!
Lovely 'Sea Dreams Villa' w/ Private Beach & Deck!
10.0 out of 10, Exceptional, (23)

Pool, 5 bdrm, sandy beach, sunsets, quiet, cabana w/hammocks, bikes, well kept
Pool, 5 bdrm, sandy beach, sunsets, quiet, cabana w/hammocks, bikes, well kept
10.0 out of 10, Exceptional, (76)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find out more about Sister Islands
Find out more about Sister Islands
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More Hotel Options in Sister Islands
- Adventure Hotels in Sister Islands
- All-inclusive Hotel in Sister Islands
- Beach Hotels in Sister Islands
- Business Hotels in Sister Islands
- Family Hotels in Sister Islands
- Historic Hotels in Sister Islands
- Hotel Wedding Venues in Sister Islands
- Hotel with a Concierge in Sister Islands
- Hotels with Bars in Sister Islands
- Hotels with Free Parking in Sister Islands
- Hotels with WiFi in Sister Islands
- Hotels with a Pool in Sister Islands
- Luxury Hotels in Sister Islands
- Pet-friendly Hotels in Sister Islands
- Romantic Hotels in Sister Islands
- Shopping Hotels in Sister Islands
More Accommodation Types in Sister Islands
- Condo Rentals in Cayman Islands
- Vacation Homes in Cayman Islands
- Apartments in Cayman Islands
- Villas in Cayman Islands
- Aparthotels in Cayman Islands
- Cottages in Cayman Islands
- Resorts in Cayman Islands
- B&B in Cayman Islands
- Guest Houses in Cayman Islands
- Condo Resorts in Cayman Islands
- Houseboats in Cayman Islands
- Lodges in Cayman Islands
- Residences in Cayman Islands
Hotels near popular Sister Islands Attractions
- Hotels near Little Cayman Beach
- Hotels near Charlie's Reef
- Hotels near Cayman Brac Bluff
- Hotels near Owen Island Beach
- Hotels near Cayman Brac Lighthouse
- Hotels near Long Beach
- Hotels near Point of Sand Beach
- Hotels near Booby Pond Nature Reserve
- Hotels near Salt Rocks Nature Trail North Trailhead
- Hotels near MV Captain Keith Tibbetts Shipwreck
Sister Islands Hotels by Star Rating
Explore more hotels
- 2-bdrm Tropical Beach Paradise w/Pool, sandy beach, cabana, wifi & more!
- Stargaze from the Hot Tub, Waterfront Luxury Private Villa with Central AC
- Nature Escape Getaway w/ in-room dining service & amenities/3bdrm 1bth/sleeps 5
- Beach Front Paradise Home. Luxurious Funishings!
- Pool, 5 bdrm, sandy beach, sunsets, quiet, cabana w/hammocks, bikes, well kept
- Blossom Village Cottage – Charming Cottage by Cayman Villas.
- Conch Club Cottage
- Ocean view from every room ,quiet neighborhood family friendly.Bluff view
- Villa, Pool, 3 Bdrms, 2.5 baths, breathtaking views, reef protected area, kayaks
- Little Cayman Escape - Stunning Views and Privacy - Call Cayman Villas!
- Sunsets, amazing sonkeling, seaside veranda, kayaks, bikes, fresh seafood 4U
- Featherstone - The Estate
- Little Cayman 3 Bedroom Oceanfront Private Villa
- Luxury Beachfront House on Cayman Brac's Nicest Beach! Vacation your way!
- POOL, ON THE WATER, 2 QN BEDS, RAISED DECK, AC, WI-FI, KAYAKS
- Southern Exposure, Secluded New Beach House on Cayman Brac! Divers delight!
- POOL w/shade sails, sand beach, beach cabana, bikes, kayaks
- Serenity On The Bay2 - Two Bed Apt Close to Supermarkets, Shops and Restaurants!
- Awesome Sea Views! Secluded Beach
- Featherstone - The Cottage