Medical Center District Vacations

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

4 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is SAR 333 per night from Mar 5 to Mar 6
SAR 333
SAR 394 total
includes taxes & fees
5 Mar - 6 Mar
8.4/10 Very Good! (2,286 reviews)
"Wish the bathroom had a exhaust fan Otherwise everything was fine"

Reviewed on 2 March 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is SAR 368 per night from Mar 16 to Mar 17
SAR 368
SAR 437 total
includes taxes & fees
16 Mar - 17 Mar
8.2/10 Very Good! (1,008 reviews)
"Great place to stay will definitely stay again"

Reviewed on 2 March 2025

San Antonio Marriott Northwest Medical Center
Clarion Pointe near Medical Center
Clarion Pointe near Medical Center
2.5 out of 5
4803 Manitou, San Antonio, TX
6.8/10 (1,571 reviews)
"Great stay thank you"

Reviewed on 3 March 2025

Get rates
Clarion Pointe near Medical Center
See all 4,282 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Medical Center District

Six Flags Fiesta Texas

Six Flags Fiesta Texas

4.5/5(970 reviews)

Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the acclaimed theater scene and entertainment choices in this family-friendly area.

Six Flags Fiesta Texas
River Walk featuring night scenes and a river or creek

River Walk

4.5/5(7,278 reviews)

River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the acclaimed theater scene and shops in this walkable area.

River Walk
Lackland Air Force Base

Lackland Air Force Base

4.5/5(1,254 reviews)

Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this family-friendly area.

Lackland Air Force Base