Medical Center District Vacations

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Where to stay in Medical Center District

Find the best Medical Center District areas and neighborhoods for the activities you enjoy most. Learn more about Medical Center District
Downtown - Riverwalk which includes heritage architecture, boating and a river or creek

Downtown San Antonio

3 out of top 10 points of interest in this area
4/5(9,525 area reviews)

Explore the heart of San Antonio with top attractions like the Alamo and River Walk, or enjoy kayaking and bicycling to the World Heritage Missions. Discover historic sites, theaters, and shopping at Rivercenter, all easily accessible by public transit.

Find hotels in Downtown San Antonio

Medical Center District Hotel Deals

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
2.5 out of 5
4431 Horizon Hill Blvd, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is SAR 333 per night from Apr 8 to Apr 9
SAR 333
SAR 394 total
includes taxes & fees
8 Apr - 9 Apr
8.4/10 Very Good! (2,384 reviews)
"Was a little strange to see quite a bit of medical people and people out side in robs"

Reviewed on 4 April 2025

La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW
San Antonio Marriott Northwest Medical Center
San Antonio Marriott Northwest Medical Center
3.5 out of 5
3233 NW Loop 410, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is SAR 357 per night from Apr 17 to Apr 18
SAR 357
SAR 425 total
includes taxes & fees
17 Apr - 18 Apr
8.2/10 Very Good! (1,003 reviews)
Getaway
"It's was a good experience for me and the family far as getting away from everyday life."

Reviewed on 2 April 2025

San Antonio Marriott Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
Drury Inn & Suites San Antonio Northwest Medical Center
3 out of 5
9806 Interstate Hwy 10 W, San Antonio, TX
Fully refundableReserve now, pay when you stay
The price is SAR 375 per night from Apr 9 to Apr 10
SAR 375
SAR 444 total
includes taxes & fees
9 Apr - 10 Apr
9.2/10 Wonderful! (1,157 reviews)
"It is very convenient to the Medical Center."

Reviewed on 4 April 2025

Drury Inn & Suites San Antonio Northwest Medical Center
See all 4,258 properties in Medical Center District
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Medical Center District

River Walk featuring night scenes and a river or creek

River Walk

4.5/5(7,278 reviews)

River Walk is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the fascinating museums and shops in this walkable area.

River Walk
Lackland Air Force Base

Lackland Air Force Base

4.5/5(1,254 reviews)

Lackland Air Force Base is just one of the places to see in San Antonio, so why not enjoy the other things to explore during your travels? Discover the entertainment venues and shops in this walkable area.

Lackland Air Force Base
Six Flags Fiesta Texas

Six Flags Fiesta Texas

4.5/5(970 reviews)

Enjoy the rides and games at Six Flags Fiesta Texas and see why this is a favorite theme park in San Antonio. Experience the lively festivals and acclaimed theater scene in this family-friendly area.

Six Flags Fiesta Texas