Find Resorts & Hotels with Spas in Lewes, DE

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Check availability on Lewes Resorts & Hotels with Spas

Compare Lewes Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Blue

3.0 star property
9.6 out of 10, Exceptional, (799)
"Staff were most helpful. Very quiet, clean, and safe. Highly recommend. Will stay again in the future."
The price is SAR 559
SAR 626 total
includes taxes & fees
1 Apr - 2 Apr
Hotel Blue

Home2 Suites by Hilton Lewes Rehoboth Beach

3.0 star property
9.4 out of 10, Exceptional, (926)
"Absolutely everything about this hotel was exceptional. Clean, amazing staff great amenities the breakfast spread was insane. Great job "
The price is SAR 312
SAR 346 total
includes taxes & fees
18 Mar - 19 Mar
Home2 Suites by Hilton Lewes Rehoboth Beach

Hyatt House Lewes/Rehoboth Beach

3.5 star property
9.4 out of 10, Exceptional, (743)
"Love love"
The price is SAR 304
SAR 337 total
includes taxes & fees
18 Mar - 19 Mar
Hyatt House Lewes/Rehoboth Beach

The Inn at Lewes

3.0 star property
6.6 out of 10, (81)
"There was a "glitch" in the reservation process. When I arrived at the property I was told it was full. However, I made another Hotels.com reservation for the night. After my trip, working with Sony at Hotels.com and the property, my full redund was processed. Thank you Inns at Lewes and Hotels.com "
The price is SAR 253
SAR 281 total
includes taxes & fees
25 Mar - 26 Mar
The Inn at Lewes

Coastal Club * 6BR New Twin Vacation Home w 3.5 Baths, Sleeps up to 14

9.6 out of 10, Exceptional, (12)
"Great stay."
Coastal Club * 6BR New Twin Vacation Home w 3.5 Baths, Sleeps up to 14

On the Beach - Lux Multi-Family House - Get the best weeks of 2025 Now!

10.0 out of 10, Exceptional, (84)
"Spacious home with nice views of the ocean. Kitchen very well stocked. Easy walk into town. Comfortable bedrooms. Oddly located on a large public parking lot but in off season it was very quiet. The address does not match Waze or the listing so double check with host on how to find the house. "
On the Beach - Lux Multi-Family House - Get the best weeks of 2025 Now!

Majestic Waterfront Condo on Rehoboth Bay Minutes From The Beach, Sleeps 8-10

9.2 out of 10, Wonderful, (15)
"This was such a gorgeous beach condo! I was in awe of the cleanliness and decor. Would definitely come back! "
The price is SAR 563
SAR 1,511 total
includes taxes & fees
12 Mar - 13 Mar
Majestic Waterfront Condo on Rehoboth Bay Minutes From The Beach, Sleeps 8-10

Clean & cozy townhome. Easy access to trails & historic Lewes. 5 mins to beach.

10.0 out of 10, Exceptional, (80)
"An amazing time! Clean house!!!"
Clean & cozy townhome. Easy access to trails & historic Lewes. 5 mins to beach.

Upscale Downtown Suite in Lewes

10.0 out of 10, Exceptional, (46)
"Where do I start….from 1st communcation with Mary until we entered the suite just easy and awesome. Mary leaves no stone unturned in the suite. The suite has everything and anything you need at anytime. The suite is so nicely decorated and comfortable, Mary thinks of everything to make your stay remarkable. The convenience of everything near by is another reason that makes her place so great.Take my word you will have a wonderful time. I look forward to returning to the suite in the near...
Upscale Downtown Suite in Lewes

Luxe Lewes Family Beach House w/ Pool & Game Room

7.2 out of 10, Good, (20)
"Wonderful property and would stay again. I tried contacting property manager to extend our stay and they never replied. "
Luxe Lewes Family Beach House w/ Pool & Game Room
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Lewes?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the historical sites and shopping in Lewes—your day trip starts here. Enjoy the museums and beaches during your vacation. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Lewes?
Among Expedia’s 294 accommodation options in Lewes, there is 1 spa hotel.
What's there to see and do in Lewes?
Experience all that Lewes has to offer when you visit Lewes Beach, Cape May - Lewes Ferry, and Cape Henlopen Beach. If you have spare time during your trip, you might want to make a stop at Cape Henlopen State Park and Lewes Historic Complex.
What is a Lewes spa hotel?
Spa hotels in Lewes provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.