Find Resorts & Hotels with Spas in Lewes, DE

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Check availability on Lewes Resorts & Hotels with Spas

Compare Lewes Resorts & Hotels with Spas room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Blue

3.0 star property
9.6 out of 10, Exceptional, (809)
"First, I have to give a shout-out to Jackie, who stayed a few minutes beyond her quitting time to get us checked in. The hotel is extremely clean and the rooms are spacious. The only beef I have is that there is a limited window for check-in and that made things a little difficult for us to get our workdays in and travel to Lewes on a Friday evening."
The price is SAR 560
SAR 627 total
includes taxes & fees
13 Apr - 14 Apr
Hotel Blue

Home2 Suites by Hilton Lewes Rehoboth Beach

3.0 star property
9.4 out of 10, Exceptional, (956)
"Good"
The price is SAR 360
SAR 399 total
includes taxes & fees
22 Apr - 23 Apr
Home2 Suites by Hilton Lewes Rehoboth Beach

Hyatt House Lewes/Rehoboth Beach

3.5 star property
9.4 out of 10, Exceptional, (775)
"Beautiful place with a nice vibe and amazing pool "
The price is SAR 357
SAR 396 total
includes taxes & fees
21 Apr - 22 Apr
Hyatt House Lewes/Rehoboth Beach

The Inn at Lewes

3.0 star property
6.6 out of 10, (81)
"There was a "glitch" in the reservation process. When I arrived at the property I was told it was full. However, I made another Hotels.com reservation for the night. After my trip, working with Sony at Hotels.com and the property, my full redund was processed. Thank you Inns at Lewes and Hotels.com "
The price is SAR 321
SAR 356 total
includes taxes & fees
24 Apr - 25 Apr
The Inn at Lewes

On the Beach - Lux Multi-Family House - Get the best weeks of 2025 Now!

10.0 out of 10, Exceptional, (86)
"Great location. Very clean. Lovely and spacious property. "
On the Beach - Lux Multi-Family House - Get the best weeks of 2025 Now!

Coastal Club * 6BR New Twin Vacation Home w 3.5 Baths, Sleeps up to 14

9.6 out of 10, Exceptional, (12)
"Great stay."
Coastal Club * 6BR New Twin Vacation Home w 3.5 Baths, Sleeps up to 14

3 bedroom family friendly condo - Winter and Spring rates are up - book early!

9.8 out of 10, Exceptional, (143)
"This is our 2nd Stay. Always cozy, great location, great beds. The kitchen is wonderful to prepare meals in. The porches are great for games, late night talks & reading. Close to everything. "
3 bedroom family friendly condo - Winter and Spring rates are up - book early!

Majestic Waterfront Condo on Rehoboth Bay Minutes From The Beach, Sleeps 8-10

9.2 out of 10, Wonderful, (15)
"This was such a gorgeous beach condo! I was in awe of the cleanliness and decor. Would definitely come back! "
The price is SAR 563
SAR 1,460 total
includes taxes & fees
11 Apr - 12 Apr
Majestic Waterfront Condo on Rehoboth Bay Minutes From The Beach, Sleeps 8-10

1st Floor Beach-town Condo. We are Pet Friendly!

9.8 out of 10, Exceptional, (22)
"Property was very clean. Some items could be replaced, such as silverware and dishes. Spices were a bonus."
1st Floor Beach-town Condo. We are Pet Friendly!

Cool Little Cottage Minutes forFrom Beaches, Shopping and Dining

10.0 out of 10, Exceptional, (127)
"Joanne was a great host and very responsive! Cottage was adorable and very nicely decorated "
Cool Little Cottage Minutes forFrom Beaches, Shopping and Dining
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking for a spa hotel in Lewes?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the historical sites and shopping in Lewes—your day trip starts here. Enjoy the museums and beaches during your vacation. Hotels with spas are the perfect way to take a break from your routine and add a layer of luxury to your weekend away.
How many spa hotels will I find in Lewes?
Among Expedia’s 294 accommodation options in Lewes, there is 1 spa hotel.
What's there to see and do in Lewes?
Experience all that Lewes has to offer when you visit Lewes Beach, Cape May - Lewes Ferry, and Cape Henlopen Beach. If you have spare time during your trip, you might want to make a stop at Cape Henlopen State Park and Lewes Historic Complex.
What is a Lewes spa hotel?
Spa hotels in Lewes provide lodging and have an on-site spa offering services like couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.