The Best Business Hotels in Greenville Downtown, SC from SAR 409 in 2025

Check availability on Greenville Downtown Business Hotels

Tonight

11 Rab. I - 12 Rab. I

Tomorrow

12 Rab. I - 13 Rab. I

This weekend

14 Rab. I - 16 Rab. I

Next weekend

21 Rab. I - 23 Rab. I

Compare Greenville Downtown Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

Full-size fridge, microwave, dishwasher, cookware/dishes/utensils

"I've stayed at Home2Suites before because I like their setup. This one was the best, my favorite. Everyone was so very friendly. It's right in the heart of downtown Greenville so prime location. I felt comfortable and safe. And it was very quiet. But I do attribute that to the other guests. Some are quieter than others. I got lucky and had the quiet ones. I highly recommend you book this place for your next Greenville stay."

SAR 677 total

includes taxes & fees

30 Mar - 31 Mar

"Desk staff were gracious and informed!"

SAR 586 total

includes taxes & fees

30 Mar - 31 Mar

"Very nice property. Super clean and kept up pretty well. Staff was very friendly."

SAR 643 total

includes taxes & fees

23 Mar - 24 Mar

"Everything was great at the hotel. I stay there yearly for a conference."

SAR 621 total

includes taxes & fees

23 Mar - 24 Mar

"Amazing Hotel and perfect location for downtown Greenville!"

SAR 642 total

includes taxes & fees

6 Apr - 7 Apr

"We chose this hotel for proximity to the Peace Center and it was well worth it. Clean comfortable room, parking right next door, excellent fitness room and on site restaurant."

SAR 541 total

includes taxes & fees

16 Mar - 17 Mar

"My wife and I had never visited Greenville. I chose The Westin hotel since it was so central to the town and its amenities. The staff and the facility more than met our needs."

SAR 803 total

includes taxes & fees

16 Mar - 17 Mar

"Good"

SAR 536 total

includes taxes & fees

30 Mar - 31 Mar

Find out more about Greenville Downtown

Recent reviews of Greenville Downtown hotels

5/5 Excellent

"My wife and I had never visited Greenville. I chose The Westin hotel since it was so central to the town and its amenities. The staff and the facility more than met our needs."

A verified traveler stayed at The Westin Poinsett Greenville

Posted 1 day ago

Home2 Suites by Hilton Greenville Downtown

5/5 Excellent

"I've stayed at Home2Suites before because I like their setup. This one was the best, my favorite. Everyone was so very friendly. It's right in the heart of downtown Greenville so prime location. I felt comfortable and safe. And it was very quiet. But I do attribute that to the other guests. Some are quieter than others. I got lucky and had the quiet ones. I highly recommend you book this place for your next Greenville stay."

A verified traveler stayed at Home2 Suites by Hilton Greenville Downtown

Posted 4 days ago