Downtown Santiago Vacations

Book a Hotel + Flight together to unlock savings

  • Plan, book, travel with confidence

  • payments icon
    Better together
    Save up to SAR 390 when you book a flight and hotel together*
    lob hotels icon
    Find the right fit
    With over 300,000 hotels worldwide, it's easy to create a perfect package
    lob packages icon
    Rest easy
    Plan, book, and manage your trip all in one place

Where to stay in Downtown Santiago

Find the best Downtown Santiago areas and neighborhoods for the activities you enjoy most. Learn more about Downtown Santiago

Downtown Santiago Hotel Deals

Almacruz Hotel y Centro de Convenciones
Almacruz Hotel y Centro de Convenciones
4 out of 5
San Antonio 65, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is SAR 284 per night from May 4 to May 5
SAR 284
SAR 284 total
includes taxes & fees
4 May - 5 May
8/10 Very Good! (553 reviews)
Perfect location great service
"Perfect place to stay in Santiago. Really beautiful hotel in a great location with friendly staff and very comfortable beds. We arrived early in the morning and they were really kind to let us check in straight away which was amazing after a long overnight flight. I would highly recommend staying ..."

Reviewed on 7 April 2025

Almacruz Hotel y Centro de Convenciones
Hotel Plaza San Francisco
Hotel Plaza San Francisco
4 out of 5
Alameda 816, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is SAR 537 per night from Apr 26 to Apr 27
SAR 537
SAR 537 total
includes taxes & fees
26 Apr - 27 Apr
9/10 Wonderful! (899 reviews)
Classic and beautiful hotel
"This hotel features a classic style. It is cozy and beautiful. Conveniently located near the San Francisco Church, the San Francisco Museum, the París-Londres Barrio, the Universidad de Chile, and the subway station, you must taste the hotel bar's amazing Pisco sour!"

Reviewed on 16 April 2025

Hotel Plaza San Francisco
Mercure Santiago Centro
Mercure Santiago Centro
3.5 out of 5
Av. Libertador Bernardo O Higgins, 632, Centro, Santiago, Region Metropolitana
Fully refundableReserve now, pay when you stay
The price is SAR 264 per night from May 10 to May 11
SAR 264
SAR 264 total
includes taxes & fees
10 May - 11 May
8.2/10 Very Good! (960 reviews)
"Good location"

Reviewed on 7 April 2025

Mercure Santiago Centro
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown Santiago