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Check prices for these dates

Compare 98 Apartments in Defiance with updated reviews, rates, and availability.

Prime Loft of Main Street

9.8 out of 10, Exceptional, (83)
"Location, Layout, View, Decor were great. Could use a deep clean"
The price is SAR 484
SAR 982 total
includes taxes & fees
31 Mar - 1 Apr
Prime Loft of Main Street

The Lofts of North Main Street

9.6 out of 10, Exceptional, (126)
"This is our 2nd time staying here for a girls weekend, and it is perfect."
The price is SAR 484
SAR 1,001 total
includes taxes & fees
7 Apr - 8 Apr
The Lofts of North Main Street

Main Street Living! 2 Bedroom Unit right On Main!

10.0 out of 10, Exceptional, (23)
"We thoroughly enjoyed our weekend stay. It was the perfect location to be able to walk historic downtown, grab food and drinks and shop the cute shops. It is also close to the casino, airport, college and TopGolf.Pros: Location, location, location :) Booking and checkin-in process were simple with excellent communication. The dedicated parking spot was nice. The house was clean, warm and had all the amenities we needed. The TVs were easy to use and the WiFi information was readily...
The price is SAR 454
SAR 1,399 total
includes taxes & fees
2 Apr - 3 Apr
Main Street Living! 2 Bedroom Unit right On Main!

The Hidden Gem - 2BR Basement Apartment on 7 Acres

9.8 out of 10, Exceptional, (8)
"Another great stay at The Hidden Gem. Easy access in a quiet location!"
The Hidden Gem - 2BR Basement Apartment on 7 Acres

Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

2.0 star property
8.0 out of 10, Very Good, (6)
"We enjoyed it! Debbie was amazing, brought firewood for us to enjoy a fire. Communication was great! The place was perfect for our family. Thank you for everything Debbie!"
The price is SAR 281
SAR 544 total
includes taxes & fees
30 Mar - 31 Mar
Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues

ENTIRE 2 BRM Apt. ON MAIN STREET...STUNNING VIEWS!!

4.0 star property
9.8 out of 10, Exceptional, (23)
"This apartment is in an outstanding location in downtown historic Saint Charles. It is very clean and the host communicates very well. I would recommend this for people looking for a location in an area where there is an abundance of shopping, food, and nightlife. It is located directly above a bar, so manage expectations when it comes to noise and ambience."
ENTIRE 2 BRM Apt. ON MAIN STREET...STUNNING VIEWS!!

The Wild West Getaway- 204-1

8.4 out of 10, Very Good, (5)
"The location was great, once we parked our car we never had to leave all weekend. Tons of shopping and wonderful restaurants just steps away. This is above a very popular bar, which was fine for us but if you have younger kids you may want something more quiet. There were doritos in the pull out sofa, other than that it was great. Parking seems to be an issue but it is a VERY popular area on the weekends so beware you may have to drive a bit to find parking. Definitely would stay again, and some...
The Wild West Getaway- 204-1

Main Street Balcony Apartment by StayLage!

9.4 out of 10, Exceptional, (28)
"Great location and comfortable stay!"
The price is SAR 506
SAR 1,686 total
includes taxes & fees
31 Mar - 1 Apr
Main Street Balcony Apartment by StayLage!

Swim, Fish, Hike, Horseback

9.6 out of 10, Exceptional, (55)
"We rented the property to be in the area for the holiday. The house had plenty of sleeping spaces and linens. The kids were enjoyed seeing the horses on the property. "
Swim, Fish, Hike, Horseback

Honky Tonk Hideaway

10.0 out of 10, Exceptional, (2)
"This property is just delightful. It was a wonderful stay with such a beautiful backyard and patio. There was a historical marker in the front yard. It was blocks from the historical downtown of St. Charles. It was within walking distance from a Starbucks and shopping in the area. "
Honky Tonk Hideaway

Cozy country setting 4 miles from route 66

10.0 out of 10, Exceptional, (4)
"Really nice property! Country setting and nice big living area."
The price is SAR 563
SAR 895 total
includes taxes & fees
23 Mar - 24 Mar
Cozy country setting 4 miles from route 66

Amazing Renovated Historic Loft on Main Street

10.0 out of 10, Exceptional, (51)
"Sister trip. Really enjoyed, place is great. I messed up our booking, but the host was super nice about the inconvenience we caused. "
The price is SAR 484
SAR 982 total
includes taxes & fees
14 Apr - 15 Apr
Amazing Renovated Historic Loft on Main Street

Stunning Modern Apartment with King Bed - 5 Mins to Creve Coeur Lake

8.0 out of 10, Very Good, (1)
"Comfortable apartment for a short stay in St Louis. All you need for your stay. We appreciated the stocked coffee bar. "
Stunning Modern Apartment with King Bed - 5 Mins to Creve Coeur Lake

Charming Duplex on Main

10.0 out of 10, Exceptional, (9)
"Everything was awesome!!!!!!"
Charming Duplex on Main

New Melle Apartment Near Missouri Wine Country

9.4 out of 10, Exceptional, (3)
"It was clean, homey and yet not too fancy! We felt right at home instantly. Loved the town and it was as described. Only 3 to 4 miles from my Aunts house. We would definately stay there again."
New Melle Apartment Near Missouri Wine Country

‘The Ruebling House’ Cozy Defiance Apartment!

9.0 out of 10, Wonderful, (23)
"Loved our stay"
‘The Ruebling House’ Cozy Defiance Apartment!

Duplex Hideaway in St. Charles, MO

10.0 out of 10, Exceptional, (4)
"The house is cute. Street parking only. Clean but small. The neighborhood was fantastic. In a historical district. Close to many shops, restaurants, and a river side park. Great place to stay with a dog."
The price is SAR 425
SAR 1,068 total
includes taxes & fees
25 Mar - 26 Mar
Duplex Hideaway in St. Charles, MO

1st Capitol Mansion - Suite 401

8.4 out of 10, Very Good, (7)
"The condo is very spacious, with plenty of beds. There are some really cool historic features in the building. Great location. And the host, John, was very helpful."
The price is SAR 371
SAR 937 total
includes taxes & fees
23 Mar - 24 Mar
1st Capitol Mansion - Suite 401

Stay on Historic Main!

9.4 out of 10, Exceptional, (23)
"My wife and I stayed for her birthday weekend and had a great time. The property is located at the end of the strip so it was perfect to start the bar hoping. The apartment was very cozy and clean. Definitely recommend for the quick get a way!!"
The price is SAR 365
SAR 894 total
includes taxes & fees
23 Mar - 24 Mar
Stay on Historic Main!

Private Basement Retreat with a HOT TUB

8.4 out of 10, Very Good, (5)
"Perfect for our needs. People do live upstairs so if you are uncomfortable with that not the place for you!"
Private Basement Retreat with a HOT TUB
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other property types in Defiance

Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.

10.0 out of 10, Exceptional, (25)
"Close to my workplace. Excellent communication with the owner should a problem arise.Will be back."
Newly Updated Charming and Cozy Home near Historic Main Street in Frenchtown.

☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome

9.0 out of 10, Wonderful, (45)
"Everything was perfect. Thank you so much for everything. "
The price is SAR 821
SAR 1,612 total
includes taxes & fees
23 Mar - 24 Mar
☆BackYard BBQ Hidden Gem☆Perfect Location~Groups /Pets Welcome

Value Suites Extended Stay - St Louis

3.0 star property
7.0 out of 10, Good, (1110)
"Great customer service "
The price is SAR 248
SAR 595 total
includes taxes & fees
23 Mar - 24 Mar
Value Suites Extended Stay - St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You’ll find 10 apartments to choose from in Defiance for your stay.
Why choose an apartment versus a traditional hotel?
Often more spacious than a traditional hotel room, an apartment includes a kitchen for convenient home-cooked meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want something in a quieter part of town.
What's a favorite apartment for a stay in Defiance?
Here are some of the top apartments in the area: The Lofts of North Main Street: Situated in St. Charles, 19.2 mi/30.8 km from the heart of Defiance. Includes free WiFi, sofa beds, and Smart TVs. Prime Loft of Main Street: Located 19.2 mi/30.9 km away in St. Charles. Free WiFi, sofa beds, and Smart TVs are included. Studio, sleeps 4, patio, short drive to Ski Resort, Six Flags & concert venues: It’s situated in Ballwin, 14.1 mi/22.7 km away. Includes Smart TVs. Main Street Living! 2 Bedroom Unit right On Main!: 18.7 mi/30.1 km away in St. Charles. ENTIRE 2 BRM Apt. ON MAIN STREET…STUNNING VIEWS!!: It’s located in St. Charles, 18.5 mi/29.7 km from Defiance. Includes private patios, sofa beds, and Smart TVs.
How many apartments will I be able to find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather during my trip to Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you’re planning an extended stay in Defiance. The hottest months are usually July and August with an average temp of 76°F, while the coldest months are January and February with an average of 38°F. Average annual precipitation for Defiance is 48 inches.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can save you time when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. You can also search for flights into St. Louis Lambert Intl. Airport (STL), which is 23.5 mi (37.8 km) away. If you’d like to explore around the area, you may want a rental car for your journey.