Find Resorts & Hotels with Spas in Cayo Santa Maria

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Pick from Cayo Santa Maria Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Frequently asked questions

Looking for a spa hotel in Cayo Santa Maria?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Check out the beaches in Cayo Santa Maria - worth a picture or two! Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your vacation.
How many spa hotels will I find in Cayo Santa Maria?
Among Expedia’s 3 accommodation options in Cayo Santa Maria, there is 1 spa hotel.
What's there to see and do in Cayo Santa Maria?
Experience Cayo Santa Maria with a stop at Playa Las Gaviotas.
What is a Cayo Santa Maria spa hotel?
Spa hotels in Cayo Santa Maria provide lodging and have an on-site spa which offers services like facials as well as beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.