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Find All Southern Illinois Hotels
We have found 968 Southern Illinois Hotels
- Holiday Inn Effingham by IHG
- TownePlace Suites by Marriott St. Louis Edwardsville, IL
- Hampton Inn & Suites St. Louis-Edwardsville
- Pinckeyville Inn and Suites
- The Principal Hotel
- Quality Inn & Suites Salem near I-57
- Days Inn by Wyndham Charleston
- TownePlace Suites by Marriott St. Louis O'Fallon
- Super 8 by Wyndham Belleville St. Louis Area
- Super 8 by Wyndham Salem
- Motel 6 Mount Vernon, IL
- Quality Inn & Suites
- Holiday Inn Express Hotel & Suites Sparta by IHG
- Suite Dreams Hotel
- Days Inn by Wyndham Troy IL
- Hotel 7 Inn Anna
- Super 8 by Wyndham Metropolis
- Comfort Inn & Suites Greenville I-70
- Fairfield Inn and Suites by Marriott Marion
- Ramada by Wyndham Vandalia
- Days Inn by Wyndham Pontoon Beach
- Welcome Suites
- Hampton Inn & Suites Effingham
- Clarion Pointe Mattoon near University
- Econo Lodge Inn & Suites
- Econo Lodge & Suites Granite City
- Best Western U. S. Inn
- University Inn of Carbondale
- Hampton Inn Collinsville
- Royal Relax Inn
- Days Inn by Wyndham Effingham
- Best Western Heartland Inn
- Americas Best Value Inn Mount Vernon
- Fairfield Inn & Suites by Marriott Mt. Vernon Rend Lake
- Motel 6 Metropolis, IL
- Quality Inn
- Budget Host Inn Greenup
- Super 8 by Wyndham Waterloo
- Americas Best Value Inn West Frankfort
- Best Western Plus Parkside Inn & Suites
- Super 8 by Wyndham Du Quoin
- Hotel 7 Vienna
- Fairfield Inn & Suites Marriott Effingham
- Days Inn by Wyndham Salem, Illinois
- Country Garden & Suites
- Super 8 by Wyndham Greenville
- Super 8 by Wyndham Okawville
- Rodeway Inn
- Wine Country Farmhouse On the Wine 🍷 Trail! Private Lake kayaks Fire Pit 🔥
- Motel 6 Troy, IL
- Eighteen-Ninety Sleepover
- Super 8 by Wyndham Mattoon
- First Western Inn
- Super 8 by Wyndham Grayville
- Indoor Heated Pool pontoon boat fish 3 full baths sleeps 17 in beds 2025 SALE!!!
- Indian Mound Motel
- SureStay Hotel by Best Western Greenville
- The Shelby Inn
- Red Bud Country Inn
- Budget Inn- Greenville
- Laketree Inn And Suites Marion
- Quality Inn
- Best Western Flora Inn
- Home2 Suites By Hilton Effingham
- Motel 6 Effingham, IL
- Super 8 by Wyndham Marshall
- Cobblestone Hotel & Suites - Newton
- Loyalty Inn Maryville
- Spillway Motel
- Baymont by Wyndham Metropolis
- Briarwood Inn
- Super 8 by Wyndham Olney
- Americas Best Value Inn Vandalia
- Gateway Inn
- Davie School Inn
- Briarwood Inn of Sparta
- Super 8 by Wyndham Mt. Carmel IL
- Illinois Historic Cross Home/Barn/Fishing/ATV/RV McLeansboro
- Bel Air Motel
- Gas Lite Motel
- The Conner House B&B
- Powhatan Motel
- Shawnee - Farmhouse on 20 acres: Beautiful Views & Hot Tub!!
- Relax Inn
- This Cobbleston Mid-Century Home Offers 4 Bedrooms on One Level
- First Western Inn Caseyville
- Upscale, Luxurious Home with Lake View and Fountains!
- Trailway Motel
- Sparta Motel
- Days Inn & Suites by Wyndham Caseyville
- Cozy Farmhouse with 4 Bedrooms and 3 Baths
- Relax Inn & Suites
- Quality Inn Cairo I-57
- Unity Lodge
- Rend Lake House only a 1/2 mile from Rend Lake Dam
- Regency Inn