Find 5 Star Hotels in Santa Rosa from SAR 351
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Santa Rosa 5 Star Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Santa Rosa 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
9.0 out of 10, Wonderful, (3817)
The price is SAR 446
SAR 491 total
includes taxes & fees
21 Apr - 22 Apr

W Panama
W Panama
8.8 out of 10, Excellent, (1006)
The price is SAR 717
SAR 789 total
includes taxes & fees
25 Apr - 26 Apr

Waldorf Astoria Panama
Waldorf Astoria Panama
9.0 out of 10, Wonderful, (1043)
The price is SAR 826
SAR 908 total
includes taxes & fees
17 Apr - 18 Apr

JW Marriott Panama
JW Marriott Panama
8.8 out of 10, Excellent, (1006)
The price is SAR 1,122
SAR 1,234 total
includes taxes & fees
25 Apr - 26 Apr

Bristol Panama, a Registry Collection Hotel
Bristol Panama, a Registry Collection Hotel
9.2 out of 10, Wonderful, (1018)
The price is SAR 622
SAR 684 total
includes taxes & fees
25 Apr - 26 Apr

Sofitel Legend Casco Viejo, Panama City
Sofitel Legend Casco Viejo, Panama City
9.8 out of 10, Exceptional, (419)
The price is SAR 1,097
SAR 1,207 total
includes taxes & fees
21 Apr - 22 Apr

Hilton Panama
Hilton Panama
8.8 out of 10, Excellent, (1071)
The price is SAR 798
SAR 878 total
includes taxes & fees
18 Apr - 19 Apr

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
9.6 out of 10, Exceptional, (554)
The price is SAR 826
SAR 909 total
includes taxes & fees
18 Apr - 19 Apr
Save an average of 15% on thousands of hotels when you're signed in
Explore similar 4-star hotels
Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Santa Rosa.

Decapolis Hotel Panama City
Avenida Balboa Con Multicentro, Panama City, Panama
The price is SAR 351 per night from Mar 30 to Mar 31
SAR 351
SAR 387 total
includes taxes & fees
30 Mar - 31 Mar
8.4/10 Very Good! (1,115 reviews)
Still don't see what you're looking for?
See all properties in Santa Rosa.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Learn more about Santa Rosa
Head to sights like Chagres River as you discover the local area in Santa Rosa.
Recent reviews of Santa Rosa hotels
Recent reviews of Santa Rosa hotels

Hotel Riu Plaza Panama
5/5 Excellent
"Beautiful and clean "
A verified traveler stayed at Hotel Riu Plaza Panama
Posted 2 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Santa Rosa Hotels by Star Rating
Stay near popular Santa Rosa attractions
- Hotels near Albrook Shopping Mall
- Hotels near Multiplaza Pacific Mall
- Hotels near Amador Causeway
- Hotels near Cinta Costera
- Hotels near Avenida Balboa
- Hotels near Colon Free Zone
- Hotels near Via Espana
- Hotels near El Dorado Mall
- Hotels near Colon 2000
- Hotels near Veracruz Beach
- Hotels near Miraflores Locks
- Hotels near Panama Viejo
- Hotels near Metromall Panama
- Hotels near Gamboa Rainforest Resort
- Hotels near Iglesia del Carmen
- Hotels near Los Pueblos Commercial Center
- Hotels near ATLAPA Conventions Center
- Hotels near Calle 50
- Hotels near Uruguay Street
- Hotels near Crown Casino
More Accommodation Types in Santa Rosa
- Apartments in Santa Rosa
- Condo Rentals in Santa Rosa
- Vacation Homes in Santa Rosa
- Aparthotels in Santa Rosa
- Hostels in Santa Rosa
- B&B in Santa Rosa
- Guest Houses in Santa Rosa
- Lodges in Santa Rosa
- Villas in Santa Rosa
- Cabin Rentals in Santa Rosa
- Cottages in Santa Rosa
- Farmstay in Santa Rosa
- Resorts in Santa Rosa
- Houseboats in Santa Rosa
- Pensions in Santa Rosa
Explore more hotels
- Sheraton Grand Panama
- Novotel Panama City
- Waldorf Astoria Panama
- Hotel Ojos del Rio
- Plaza Paitilla Inn Hotel
- TRYP by Wyndham Panamá Centro
- Las Americas Golden Tower Panama
- Sofitel Legend Casco Viejo, Panama City
- Hospedium Princess Hotel Panama
- Bristol Panama, a Registry Collection Hotel
- Holiday Inn Panama Distrito Financiero by IHG
- Hilton Panama
- Central Hotel Panama Casco Viejo
- Studio Coliving
- Waymore Hotel Spa & Casino
- MARINN PLACE Financial District
- The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
- Residence Inn by Marriott Panama City
- AC Hotel by Marriott Panama City
- American Trade Hotel