Find 4 Star Hotels in Opelousas, LA from SAR 376
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check availability on Opelousas 4 Star Hotels
Tonight
Tomorrow
This weekend
Next weekend
Compare Opelousas 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

DoubleTree by Hilton Hotel Lafayette
DoubleTree by Hilton Hotel Lafayette
8.2 out of 10, Very Good, (1014)
The price is SAR 376
SAR 433 total
includes taxes & fees
6 Apr - 7 Apr

Maison D'Memoire Bed & Breakfast Cottages
Maison D'Memoire Bed & Breakfast Cottages
9.6 out of 10, Exceptional, (91)
The price is SAR 747
SAR 846 total
includes taxes & fees
12 Mar - 13 Mar

Wyndham Garden Lafayette
Wyndham Garden Lafayette
5.4 out of 10, (548)
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Opelousas
Experience the history, casinos, and cafes in Opelousas!

Recent reviews of Opelousas hotels
Recent reviews of Opelousas hotels

DoubleTree by Hilton Hotel Lafayette
5/5 Excellent
Mardi Gras Stay
"It was a great experience, very nice, clean, and welcoming! "
A verified traveler stayed at DoubleTree by Hilton Hotel Lafayette
Posted 4 days ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Opelousas Hotels by Star Rating
Stay near popular Opelousas attractions
- Hotels near Evangeline Downs Racetrack & Casino
- Hotels near St. Landry Catholic Church
- Hotels near Louisiana Orphan Train Museum
- Hotels near Cajundome
- Hotels near University of Louisiana at Lafayette
- Hotels near Acadian Village
- Hotels near CIty Club at River Ranch
- Hotels near Moore Park
- Hotels near Cajun Field
- Hotels near Vermilionville
- Hotels near Acadiana Mall
More Hotel Options in Opelousas
- Adventure Hotels in Opelousas
- Business Hotels in Opelousas
- Casinos in Opelousas
- Cheap Hotels in Opelousas
- Family Hotels in Opelousas
- Golf Hotels in Opelousas
- Historic Hotels in Opelousas
- Hotel Wedding Venues in Opelousas
- Hotels with Bars in Opelousas
- Hotels with Free Parking in Opelousas
- Hotels with Hot Tubs in Opelousas
- Hotels with WiFi in Opelousas
- Hotels with a Pool in Opelousas
- Hotels with an Indoor Pool in Opelousas
- Hotels with smoking rooms in Opelousas
- Pet-friendly Hotels in Opelousas
- Resorts & Hotels with Spas in Opelousas
- Shopping Hotels in Opelousas
Explore more hotels
- Staybridge Suites Lafayette by IHG
- Smart Stay Inn
- Tru by Hilton Lafayette River Ranch
- Candlewood Suites Lafayette - River Ranch by IHG
- Holiday Inn Express Hotel & Suites Lafayette by IHG
- Holiday Inn Hotel & Suites Lafayette North by IHG
- Howard Johnson by Wyndham Scott Lafayette
- Holiday Inn Express Hotel & Suites Lafayette South by IHG
- Hilton Garden Inn Lafayette/Cajundome
- Spark by Hilton Lafayette South
- Comfort Suites Oil Center
- Quality Inn & Suites Lafayette
- Fairfield Inn & Suites by Marriott Lafayette South
- Homewood Suites by Hilton Lafayette, LA
- WoodSpring Suites Lafayette
- Home2 Suites by Hilton Parc Lafayette
- Drury Inn & Suites Lafayette, LA
- TownePlace Suites by Marriott Lafayette South
- SpringHill Suites by Marriott Lafayette South at River Ranch
- Days Inn by Wyndham Lafayette Near Lafayette Airport